Embryonic Stem ­Cells - Recent ­Advances in Plu­ripotent Stem C­ell-Based Regen­erative Medicin­e

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Also, great hopes are linked to using stem cells as a tool for drug discovery. In order to make progress towards commercialization, researchers in the field are evaluating standardization of their cultivation and efficient scale-up. At our 3rd Stem Cell Community Day, which will take place on November, 21 in Lisbon, Portugal, we will again bring together experts from industry and academia to discuss recent achievements, challenges, and chances in stem cell bioprocessing for research and commercial manufacturing. Registration is for free. Submit your poster abstract and have the chance to win 1, EUR.

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Visit our event website to get more information about the program and confirmed speakers. For many applications like disease modeling, drug toxicity assessment, and manufacture of stem cell-based products, three-dimensional 3D cell aggregates are of great interest.

Download application note PDF. Widely established in traditional cell culture, controlled bioreactors have the potential to establish reproducible expansion of stem cells. They provide extensive options for monitoring and control of key parameters such as pH and dissolved oxygen in real-time and facilitate a controlled differentiation of the cells.

Through scalable bioreactor design, results obtained in small scale can be transferred to larger working volumes while maintaining optimum mass transfer.

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Frontiers | Therapeutic Application of Pluripotent Stem Cells: Challenges and Risks | Medicine

Our infield application specialist Dr. Download interview PDF. Since the pioneering development of cell reprogramming by Shinya Yamanaka in , induced pluripotent stem cells iPSCs have risen to be the most promising alternative to ethically problematic embryonic stem cells. Controlled cultivation and scale-up in clinical grade as well as ways to control their differentiation towards their final destiny will be key steps towards commercial use of these cells.

Robert Zweigerdt and his team at Hannover Medical School are investigating human pluripotent stem cell culture for clinical use.


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Mesenchymal stem cells MSCs are multipotent cells derived from the bone marrow, from adipose tissue, cord blood or other tissues related to the embryonic mesoderm. They are relatively easy to obtain and have great potential for cell therapy and drug screening. Biomass derived in that way has been used in a Phase 1 clinical trial.


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Download presentation PDF. The Stem Cell Community Day connects researchers from all over the world to review recent advances in the area of stem cells, with a special focus on cultivation in stirred-tank bioreactors.

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References

Publishing Information Stem Cells Portal. Cesario V. Borlongan, et al. Email or Customer ID. Forgot password? Old Password. New Password.

Embryonic Stem Cells

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